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Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila
Autophagy delivers cytoplasmic material for lysosomal degradation in eukaryotic cells. Starvation induces high levels of autophagy to promote survival in the lack of nutrients. We compared genome-wide transcriptional profiles of fed and starved control, autophagy-deficient Atg7 and Atg1 null mutant...
Autores principales: | Érdi, Balázs, Nagy, Péter, Zvara, Ágnes, Varga, Ágnes, Pircs, Karolina, Ménesi, Dalma, Puskás, László G., Juhász, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429548/ https://www.ncbi.nlm.nih.gov/pubmed/22562043 http://dx.doi.org/10.4161/auto.20069 |
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