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Can the exome and the immunome converge on the design of efficient cancer vaccines?
Human cancers carry hundreds of non-synonymous mutations, several dozens among which may lead to the generation of tumor-specific MHC Class I-restricted epitopes. Hence every patient’s tumor harbors a highly specific mutational and antigenic signature and up to 95% of these mutations are unique. Thi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429561/ https://www.ncbi.nlm.nih.gov/pubmed/22934249 http://dx.doi.org/10.4161/onci.20730 |