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The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis
Vav1 is expressed exclusively in hematopoietic cells and is required for T cell development and activation. Vav1-deficient mice show thymic hypocellularity due to a partial block during thymocyte development at the DN3 stage and between the double positive (DP) and single positive (SP) transition. V...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429564/ https://www.ncbi.nlm.nih.gov/pubmed/22934252 http://dx.doi.org/10.4161/onci.20225 |