Cargando…

Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination

Tumor specific antigens (TSA) provide an opportunity to mobilize therapeutic immune responses against cancer. To evade such responses, tumor development in immunocompetent hosts is accompanied by acquisition of both active and passive mechanisms of immune suppression, including recruitment of CD4+Fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Schreiber, Taylor H., Wolf, Dietlinde, Bodero, Maria, Podack, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429568/
https://www.ncbi.nlm.nih.gov/pubmed/22934256
http://dx.doi.org/10.4161/onci.20298