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Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination
Tumor specific antigens (TSA) provide an opportunity to mobilize therapeutic immune responses against cancer. To evade such responses, tumor development in immunocompetent hosts is accompanied by acquisition of both active and passive mechanisms of immune suppression, including recruitment of CD4+Fo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429568/ https://www.ncbi.nlm.nih.gov/pubmed/22934256 http://dx.doi.org/10.4161/onci.20298 |