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TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b

Tumor cells expressing TLRs is generally recognized to mediate tumor inflammation. However, whether and how tumor TLR signaling pathways negatively regulate tumor inflammation remains unclear. In this report, we find that TLR4 signaling of H22 hepatocarcinoma tumor cells is transduced through MyD88...

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Detalles Bibliográficos
Autores principales: Li, Dapeng, Jia, Haibo, Zhang, Huafeng, Lv, Meng, Liu, Jing, Zhang, Yi, Huang, Tao, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429572/
https://www.ncbi.nlm.nih.gov/pubmed/22934260
http://dx.doi.org/10.4161/onci.19854