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Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

Regulatory T cells (Treg) have been reported of poor prognosis for overall survival in primary breast tumors (BT). As CCL22 plays a major role in Treg recruitment within primary BT we deciphered the mechanisms involved in the CCL22 production by breast epithelial tumor cells and propose herein the m...

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Detalles Bibliográficos
Autores principales: Ménétrier-Caux, Christine, Faget, Julien, Biota, Cathy, Gobert, Michael, Blay, Jean-Yves, Caux, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429586/
https://www.ncbi.nlm.nih.gov/pubmed/22934274
http://dx.doi.org/10.4161/onci.19680