Cargando…

Antagonizing the innate pattern recognition receptor CD204 to improve dendritic cell-targeted cancer immunotherapy

Extensive studies have established a role of scavenger receptor CD204 in pattern recognition and ligand uptake. Strikingly, we recently revealed a previously unrecognized feature of CD204 action in attenuating T-cell activation and antitumor immunity. Blocking its activity in dendritic cells represe...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Xiaofei, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429590/
https://www.ncbi.nlm.nih.gov/pubmed/22934278
http://dx.doi.org/10.4161/onci.19728