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Development of a novel universal immune receptor for antigen targeting: To Infinity and beyond
Chimeric antigen receptors (CARs) possess fixed specificity for a single antigen and require empirical testing in T cells. To address this, we have developed a novel, adaptable immune receptor strategy that allows for the rapid generation and testing of T cells of nearly infinite antigen specificity...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429592/ https://www.ncbi.nlm.nih.gov/pubmed/22934280 http://dx.doi.org/10.4161/onci.19730 |