Cargando…

Synergistic induction of cancer cell migration regulated by Gβγ and phosphatidylinositol 3-kinase

Phosphatidylinositol 3-kinase (PI3K) is essential for both G protein-coupled receptor (GPCR)- and receptor tyrosine kinase (RTK)-mediated cancer cell migration. Here, we have shown that maximum migration is achieved by full activation of phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchang...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun Kyoung, Yun, Sung Ji, Ha, Jung Min, Kim, Young Whan, Jin, In Hye, Woo, Dae Han, Lee, Hye Sun, Ha, Hong Koo, Bae, Sun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429812/
https://www.ncbi.nlm.nih.gov/pubmed/22627809
http://dx.doi.org/10.3858/emm.2012.44.8.055