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Synergistic induction of cancer cell migration regulated by Gβγ and phosphatidylinositol 3-kinase
Phosphatidylinositol 3-kinase (PI3K) is essential for both G protein-coupled receptor (GPCR)- and receptor tyrosine kinase (RTK)-mediated cancer cell migration. Here, we have shown that maximum migration is achieved by full activation of phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchang...
Autores principales: | Kim, Eun Kyoung, Yun, Sung Ji, Ha, Jung Min, Kim, Young Whan, Jin, In Hye, Woo, Dae Han, Lee, Hye Sun, Ha, Hong Koo, Bae, Sun Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429812/ https://www.ncbi.nlm.nih.gov/pubmed/22627809 http://dx.doi.org/10.3858/emm.2012.44.8.055 |
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