Cargando…

Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture

Human bone marrow mesenchymal stem cells (MSCs) expanded in vitro exhibit not only a tendency to lose their proliferative potential, homing ability and telomere length but also genetic or epigenetic modifications, resulting in senescence. We compared differential methylation patterns of genes and mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Mi Ran, In, Yong-Ho, Park, Jungsun, Park, Taesung, Jung, Kyoung Hwa, Chai, Jin Choul, Chung, Mi Kyung, Lee, Young Seek, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429814/
https://www.ncbi.nlm.nih.gov/pubmed/22684242
http://dx.doi.org/10.3858/emm.2012.44.8.057