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Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture
Human bone marrow mesenchymal stem cells (MSCs) expanded in vitro exhibit not only a tendency to lose their proliferative potential, homing ability and telomere length but also genetic or epigenetic modifications, resulting in senescence. We compared differential methylation patterns of genes and mi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429814/ https://www.ncbi.nlm.nih.gov/pubmed/22684242 http://dx.doi.org/10.3858/emm.2012.44.8.057 |