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Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility

Human FACT (facilitates chromatin transcription) consists of the proteins SPT16 and SSRP1 and acts as a histone chaperone in the (dis)assembly of nucleosome (and thereby chromatin) structure during transcription and DNA replication. We identified a Plasmodium berghei protein, termed FACT-L, with hom...

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Detalles Bibliográficos
Autores principales: Laurentino, Eliane C, Taylor, Sonya, Mair, Gunnar R, Lasonder, Edwin, Bartfai, Richard, Stunnenberg, Hendrik G, Kroeze, Hans, Ramesar, Jai, Franke-Fayard, Blandine, Khan, Shahid M, Janse, Chris J, Waters, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429858/
https://www.ncbi.nlm.nih.gov/pubmed/21899698
http://dx.doi.org/10.1111/j.1462-5822.2011.01683.x