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Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility
Human FACT (facilitates chromatin transcription) consists of the proteins SPT16 and SSRP1 and acts as a histone chaperone in the (dis)assembly of nucleosome (and thereby chromatin) structure during transcription and DNA replication. We identified a Plasmodium berghei protein, termed FACT-L, with hom...
Autores principales: | Laurentino, Eliane C, Taylor, Sonya, Mair, Gunnar R, Lasonder, Edwin, Bartfai, Richard, Stunnenberg, Hendrik G, Kroeze, Hans, Ramesar, Jai, Franke-Fayard, Blandine, Khan, Shahid M, Janse, Chris J, Waters, Andrew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429858/ https://www.ncbi.nlm.nih.gov/pubmed/21899698 http://dx.doi.org/10.1111/j.1462-5822.2011.01683.x |
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