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Pseudomonas aeruginosa pilin activates the inflammasome

IL-1β is produced from inactive pro-IL-1β by activation of caspase-1 brought about by a multi-subunit protein platform called the inflammasome. Many bacteria can trigger inflammasome activity through flagellin activation of the host protein NLRC4. However, strains of the common human pathogen Pseudo...

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Detalles Bibliográficos
Autores principales: Lindestam Arlehamn, Cecilia S, Evans, Tom J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429865/
https://www.ncbi.nlm.nih.gov/pubmed/20955240
http://dx.doi.org/10.1111/j.1462-5822.2010.01541.x