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Predicting effects of structural stress in a genome-reduced model bacterial metabolism

Mycoplasma pneumoniae is a human pathogen recently proposed as a genome-reduced model for bacterial systems biology. Here, we study the response of its metabolic network to different forms of structural stress, including removal of individual and pairs of reactions and knockout of genes and clusters...

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Detalles Bibliográficos
Autores principales: Güell, Oriol, Sagués, Francesc, Serrano, M. Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429883/
https://www.ncbi.nlm.nih.gov/pubmed/22934134
http://dx.doi.org/10.1038/srep00621