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The Lsktm1 Locus Modulates Lung and Skin Tumorigenesis in the Mouse

Alleles derived from skin tumor−resistant Car-R mice provide resistance to both skin and lung tumorigenesis over the susceptibility of the SWR/J strain. In an effort to map tumor modifier loci affecting both tumor types, we carried out a genetic linkage analysis in backcross SWR/J x (SWR/J x Car-R)...

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Detalles Bibliográficos
Autores principales: Galvan, Antonella, Colombo, Francesca, Noci, Sara, Pazzaglia, Simonetta, Mancuso, Mariateresa, Manenti, Giacomo, Broman, Karl W., Saran, Anna, Dragani, Tommaso A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429918/
https://www.ncbi.nlm.nih.gov/pubmed/22973541
http://dx.doi.org/10.1534/g3.112.003525