Evolutionary History and Genome Organization of DUF1220 Protein Domains

DUF1220 protein domains exhibit the most extreme human lineage–specific (HLS) copy number increase of any protein coding region in the human genome and have recently been linked to evolutionary and pathological changes in brain size (e.g., 1q21‐associated microcephaly). These findings lend support t...

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Detalles Bibliográficos
Autores principales: O’Bleness, Majesta S., Dickens, C. Michael, Dumas, Laura J., Kehrer-Sawatzki, Hildegard, Wyckoff, Gerald J., Sikela, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429928/
https://www.ncbi.nlm.nih.gov/pubmed/22973535
http://dx.doi.org/10.1534/g3.112.003061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429928/
https://www.ncbi.nlm.nih.gov/pubmed/22973535
http://dx.doi.org/10.1534/g3.112.003061

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