Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Airway mucin secretion and MC (mast cell) degranulation must be tightly controlled for homoeostasis of the lungs and immune system respectively. We found the exocytic protein Munc18b to be highly expressed in mouse airway epithelial cells and MCs, and localized to the apical pole of airway secretory...

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Detalles Bibliográficos
Autores principales: Kim, Kyubo, Petrova, Youlia M., Scott, Brenton L., Nigam, Rupesh, Agrawal, Anurag, Evans, Christopher M., Azzegagh, Zoulikha, Gomez, Alejandra, Rodarte, Elsa M., Olkkonen, Vesa M., Bagirzadeh, Rustam, Piccotti, Lucia, Ren, Binhui, Yoon, Joo-Heon, McNew, James A., Adachi, Roberto, Tuvim, Michael J., Dickey, Burton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430001/
https://www.ncbi.nlm.nih.gov/pubmed/22694344
http://dx.doi.org/10.1042/BJ20120057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430001/
https://www.ncbi.nlm.nih.gov/pubmed/22694344
http://dx.doi.org/10.1042/BJ20120057

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