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Can repeated exposure to morphine change the spinal analgesic effects of lidocaine in rats?*

BACKGROUND: Chronic opium exposure leads to altered response to opioid compounds. The aim of this study was to assess the behavioral effects of opium tolerance on the analgesic effects of intrathecal lidocaine in rats. METHODS: Twenty-four adult male Sprague Dawley rats with intrathecal (IT) cathete...

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Detalles Bibliográficos
Autores principales: Dabbagh, Ali, Moghadam, Shervin Farkhondehkish, Rajaei, Samira, Mansouri, Zahra, Manaheji, Homa Shardi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430028/
https://www.ncbi.nlm.nih.gov/pubmed/22973332