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The protective role of endogenous nitric oxide donor (L-arginine) in cisplatin-induced nephrotoxicity: Gender related differences in rat model

BACKGROUND: Cisplatin (CP) as a potential drug for solid tumors produces nephrotoxicity and disturbs endothelial function. CP induced nephrotoxicity may be gender related. Nitric oxide plays a pivotal role in endothelial function and L-arginine as endogenous NO donor promotes endothelial function. T...

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Detalles Bibliográficos
Autores principales: Eshraghi-Jazi, Fatemeh, Nematbakhsh, Mehdi, Nasri, Hamid, Talebi, Ardeshir, Haghighi, Maryam, Pezeshki, Zahra, Safari, Tahereh, Ashrafi, Farzaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430054/
https://www.ncbi.nlm.nih.gov/pubmed/22973338