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Paternal Benzo[a]pyrene Exposure Affects Gene Expression in the Early Developing Mouse Embryo
The health of the offspring depends on the genetic constitution of the parental germ cells. The paternal genome appears to be important; e.g., de novo mutations in some genes seem to arise mostly from the father, whereas epigenetic modifications of DNA and histones are frequent in the paternal gonad...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430208/ https://www.ncbi.nlm.nih.gov/pubmed/22641617 http://dx.doi.org/10.1093/toxsci/kfs187 |