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Structural Analysis of Cytochrome P450 105N1 Involved in the Biosynthesis of the Zincophore, Coelibactin

Coelibactin is a putative non-ribosomally synthesized peptide with predicted zincophore activity and which has been implicated in antibiotic regulation in Streptomyces coelicolor A3(2). The coelibactin biosynthetic pathway contains a stereo- and regio-specific monooxygenation step catalyzed by a cyt...

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Detalles Bibliográficos
Autores principales: Zhao, Bin, Moody, Suzy C., Hider, Robert C., Lei, Li, Kelly, Steven L., Waterman, Michael R., Lamb, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430247/
https://www.ncbi.nlm.nih.gov/pubmed/22942716
http://dx.doi.org/10.3390/ijms13078500