Mitochondrial Dysfunction and Oxidative Stress Promote Apoptotic Cell Death in the Striatum via Cytochrome c/Caspase-3 Signaling Cascade Following Chronic Rotenone Intoxication in Rats

Parkinson’s disease (PD) is a progressive neurological disorder marked by nigrostriatal dopaminergic degeneration. Evidence suggests that mitochondrial dysfunction may be linked to PD through a variety of different pathways, including free-radical generation and dysfunction of the mitochondrial Comp...

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Detalles Bibliográficos
Autores principales: Lin, Tsu-Kung, Cheng, Ching-Hsiao, Chen, Shang-Der, Liou, Chia-Wei, Huang, Chi-Ren, Chuang, Yao-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430261/
https://www.ncbi.nlm.nih.gov/pubmed/22942730
http://dx.doi.org/10.3390/ijms13078722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430261/
https://www.ncbi.nlm.nih.gov/pubmed/22942730
http://dx.doi.org/10.3390/ijms13078722

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