Oxidative stress due to radiation in CD34(+) Hematopoietic progenitor cells: protection by IGF-1

Radiation exerts direct as well as indirect effects on DNA through the generation of reactive oxygen species (ROS). Irradiated hematopoietic progenitor cells (HPCs) experience DNA strand breaks, favoring genetic instability, due to ROS generation. Our aim was to study the effect of a range of radiat...

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Detalles Bibliográficos
Autores principales: Floratou, Konstantina, Giannopoulou, Efstathia, Antonacopoulou, Anna, Karakantza, Marina, Adonakis, George, Kardamakis, Dimitrios, Matsouka, Panagiota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430413/
https://www.ncbi.nlm.nih.gov/pubmed/22843358
http://dx.doi.org/10.1093/jrr/rrs019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430413/
https://www.ncbi.nlm.nih.gov/pubmed/22843358
http://dx.doi.org/10.1093/jrr/rrs019

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