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Oxidative stress due to radiation in CD34(+) Hematopoietic progenitor cells: protection by IGF-1
Radiation exerts direct as well as indirect effects on DNA through the generation of reactive oxygen species (ROS). Irradiated hematopoietic progenitor cells (HPCs) experience DNA strand breaks, favoring genetic instability, due to ROS generation. Our aim was to study the effect of a range of radiat...
Autores principales: | Floratou, Konstantina, Giannopoulou, Efstathia, Antonacopoulou, Anna, Karakantza, Marina, Adonakis, George, Kardamakis, Dimitrios, Matsouka, Panagiota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430413/ https://www.ncbi.nlm.nih.gov/pubmed/22843358 http://dx.doi.org/10.1093/jrr/rrs019 |
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