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Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation

BACKGROUND: Immunosuppressants such as mycophenolate mofetil (MMF) have the capacity to inhibit microglial and astrocytic activation and to reduce the extent of cell death after neuronal injury. This study was designed to determine the effective neuroprotective time frame in which MMF elicits its be...

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Detalles Bibliográficos
Autores principales: Ebrahimi, Fahim, Koch, Marco, Pieroh, Philipp, Ghadban, Chalid, Hobusch, Constance, Bechmann, Ingo, Dehghani, Faramarz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430572/
https://www.ncbi.nlm.nih.gov/pubmed/22569136
http://dx.doi.org/10.1186/1742-2094-9-89