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Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation
BACKGROUND: Immunosuppressants such as mycophenolate mofetil (MMF) have the capacity to inhibit microglial and astrocytic activation and to reduce the extent of cell death after neuronal injury. This study was designed to determine the effective neuroprotective time frame in which MMF elicits its be...
Autores principales: | Ebrahimi, Fahim, Koch, Marco, Pieroh, Philipp, Ghadban, Chalid, Hobusch, Constance, Bechmann, Ingo, Dehghani, Faramarz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430572/ https://www.ncbi.nlm.nih.gov/pubmed/22569136 http://dx.doi.org/10.1186/1742-2094-9-89 |
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