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Tolerance Induction by Exosomes from Immature Dendritic Cells and Rapamycin in a Mouse Cardiac Allograft Model

BACKGROUND: Dendritic cells (DCs) release bioactive exosomes that play an important role in immune regulation. Because they express low levels of class I major histocompatibility complex (MHC) and co-stimulatory molecules, exosomes derived from donor immature DCs (imDex) prolong allograft survival b...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Li, Jun-Jie, Yang, Jing-Yue, Wang, De-Sheng, Zhao, Wei, Song, Wen-Jie, Li, Wei-Min, Wang, Jian-Feng, Han, Wei, Zhang, Zhuo-Chao, Yu, Yong, Cao, Da-Yong, Dou, Ke-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430614/
https://www.ncbi.nlm.nih.gov/pubmed/22952868
http://dx.doi.org/10.1371/journal.pone.0044045