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The Largely Normal Response to Toll-Like Receptor 7 and 9 Stimulation and the Enhanced Expression of SIGIRR by B Cells in Systemic Lupus Erythematosus

BACKGROUND: Altered Toll-like receptor (TLR) signaling has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). The present study was undertaken to characterize responses of B cells from SLE patients to TLR7 and TLR9 stimulation and to explore the potential role of single immun...

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Detalles Bibliográficos
Autores principales: Zhu, Yun-Yan, Su, Yin, Li, Zhan-Guo, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430643/
https://www.ncbi.nlm.nih.gov/pubmed/22952899
http://dx.doi.org/10.1371/journal.pone.0044131