Cargando…

Betaglycan (TβRIII) Is Expressed in the Thymus and Regulates T Cell Development by Protecting Thymocytes from Apoptosis

TGF-β type III receptor (TβRIII) is a coreceptor for TGFβ family members required for high-affinity binding of these ligands to their receptors, potentiating their cellular functions. TGF-β [1]–[3], bone morphogenetic proteins (BMP2/4) and inhibins regulate different checkpoints during T cell differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Aleman-Muench, German R., Mendoza, Valentin, Stenvers, Kaye, Garcia-Zepeda, Eduardo A., Lopez-Casillas, Fernando, Raman, Chander, Soldevila, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430661/
https://www.ncbi.nlm.nih.gov/pubmed/22952931
http://dx.doi.org/10.1371/journal.pone.0044217