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Betaglycan (TβRIII) Is Expressed in the Thymus and Regulates T Cell Development by Protecting Thymocytes from Apoptosis
TGF-β type III receptor (TβRIII) is a coreceptor for TGFβ family members required for high-affinity binding of these ligands to their receptors, potentiating their cellular functions. TGF-β [1]–[3], bone morphogenetic proteins (BMP2/4) and inhibins regulate different checkpoints during T cell differ...
Autores principales: | Aleman-Muench, German R., Mendoza, Valentin, Stenvers, Kaye, Garcia-Zepeda, Eduardo A., Lopez-Casillas, Fernando, Raman, Chander, Soldevila, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430661/ https://www.ncbi.nlm.nih.gov/pubmed/22952931 http://dx.doi.org/10.1371/journal.pone.0044217 |
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