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A Resealed-Cell System for Analyzing Pathogenic Intracellular Events: Perturbation of Endocytic Pathways under Diabetic Conditions

Cell-based assay systems that can serve as cellular models of aberrant function in pathogenic organs would be novel and useful tools for screening drugs and clarifying the molecular mechanisms of various diseases. We constructed model cells that replicated the conditions in diabetic hepatocytes by u...

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Detalles Bibliográficos
Autores principales: Kano, Fumi, Nakatsu, Daiki, Noguchi, Yoshiyuki, Yamamoto, Akitsugu, Murata, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430665/
https://www.ncbi.nlm.nih.gov/pubmed/22952896
http://dx.doi.org/10.1371/journal.pone.0044127