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A Resealed-Cell System for Analyzing Pathogenic Intracellular Events: Perturbation of Endocytic Pathways under Diabetic Conditions
Cell-based assay systems that can serve as cellular models of aberrant function in pathogenic organs would be novel and useful tools for screening drugs and clarifying the molecular mechanisms of various diseases. We constructed model cells that replicated the conditions in diabetic hepatocytes by u...
Autores principales: | Kano, Fumi, Nakatsu, Daiki, Noguchi, Yoshiyuki, Yamamoto, Akitsugu, Murata, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430665/ https://www.ncbi.nlm.nih.gov/pubmed/22952896 http://dx.doi.org/10.1371/journal.pone.0044127 |
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