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Interferon Gamma and Sonic Hedgehog Signaling Are Required to Dysregulate Murine Neural Stem/Precursor Cells

BACKGROUND: The pro-inflammatory cytokine interferon gamma (IFNγ), a key player in various neurological diseases, was recently shown to induce a dysregulated phenotype in neural stem/precursor cells (NSPCs) that is characterized by the simultaneous expression of glial and neuronal markers and irregu...

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Detalles Bibliográficos
Autores principales: Walter, Janine, Hartung, Hans-Peter, Dihné, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430684/
https://www.ncbi.nlm.nih.gov/pubmed/22952668
http://dx.doi.org/10.1371/journal.pone.0043338