The N-terminus of mature human frataxin is intrinsically unfolded

Frataxin is a highly conserved nuclear-encoded mitochondrial protein whose deficiency is the primary cause of Friedreich’s ataxia, an autosomal recessive neurodegenerative disease. The frataxin structure comprises a well-characterized globular domain that is present in all species and is preceded in...

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Detalles Bibliográficos
Autores principales: Prischi, Filippo, Giannini, Clelia, Adinolfi, Salvatore, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430858/
https://www.ncbi.nlm.nih.gov/pubmed/19843162
http://dx.doi.org/10.1111/j.1742-4658.2009.07381.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430858/
https://www.ncbi.nlm.nih.gov/pubmed/19843162
http://dx.doi.org/10.1111/j.1742-4658.2009.07381.x

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