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The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor

The Erwinia ligand-gated ion channel (ELIC) is a bacterial homologue of vertebrate Cys-loop ligand-gated ion channels. It is activated by GABA, and this property, combined with its structural similarity to GABA(A) and other Cys-loop receptors, makes it potentially an excellent model to probe their s...

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Detalles Bibliográficos
Autores principales: Thompson, Andrew J., Alqazzaz, Mona, Ulens, Chris, Lummis, Sarah C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430861/
https://www.ncbi.nlm.nih.gov/pubmed/22677470
http://dx.doi.org/10.1016/j.neuropharm.2012.05.027