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The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor
The Erwinia ligand-gated ion channel (ELIC) is a bacterial homologue of vertebrate Cys-loop ligand-gated ion channels. It is activated by GABA, and this property, combined with its structural similarity to GABA(A) and other Cys-loop receptors, makes it potentially an excellent model to probe their s...
Autores principales: | Thompson, Andrew J., Alqazzaz, Mona, Ulens, Chris, Lummis, Sarah C.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430861/ https://www.ncbi.nlm.nih.gov/pubmed/22677470 http://dx.doi.org/10.1016/j.neuropharm.2012.05.027 |
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