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Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge

BACKGROUND: The corticotropin-releasing factor type 2 receptor (CRFR2) is suggested to play an important role in aiding recovery from acute stress, but any chronic effects of CRFR2 activation are unknown. CRFR2 in the midbrain raphé nuclei modulate serotonergic activity of this key source of seroton...

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Detalles Bibliográficos
Autores principales: Neufeld-Cohen, Adi, Kelly, Paul A.T., Paul, Evan D., Carter, Roderick N., Skinner, Elizabeth, Olverman, Henry J., Vaughan, Joan M., Issler, Orna, Kuperman, Yael, Lowry, Christopher A., Vale, Wylie W., Seckl, Jonathan R., Chen, Alon, Jamieson, Pauline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430862/
https://www.ncbi.nlm.nih.gov/pubmed/22704666
http://dx.doi.org/10.1016/j.biopsych.2012.05.005