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Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2
A central feature of TB pathogenesis is the formation of Mycobacterium tuberculosis latent infections that can persist for decades. Nitric oxide produced by infected lung macrophages promotes expression of genes associated with dormancy, and impaired nitric oxide production can lead to reactivation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Churchill Livingstone
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430963/ https://www.ncbi.nlm.nih.gov/pubmed/22464736 http://dx.doi.org/10.1016/j.tube.2012.03.001 |