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Oral Metformin Treatment Prevents Enhanced Insulin Demand and Placental Dysfunction in the Pregnant Rat Fed a Fructose-Rich Diet

The intake of a fructose-rich diet (FRD) in the normal female rat induces features similar to those observed in the human metabolic syndrome phenotype. We studied the impact of FRD administration to mothers on pregnancy outcome. On gestational day (Gd) zero rats were assigned to either group: ad lib...

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Detalles Bibliográficos
Autores principales: Alzamendi, Ana, Del Zotto, Hector, Castrogiovanni, Daniel, Romero, Jose, Giovambattista, Andres, Spinedi, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431097/
https://www.ncbi.nlm.nih.gov/pubmed/22957268
http://dx.doi.org/10.5402/2012/757913