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Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors

Inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) is considered a promising strategy for the treatment of Alzheimer's disease (AD). This research project aims to provide a comprehensive knowledge of newly synthesized coumarin analogues with anti-AD potential. In the pre...

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Detalles Bibliográficos
Autores principales: Raza, Ahsan, Saeed, Aamer, Ibrar, Aliya, Muddassar, Muhammad, Khan, Aftab Ahmed, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431135/
https://www.ncbi.nlm.nih.gov/pubmed/22966467
http://dx.doi.org/10.5402/2012/707932