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Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2)

BACKGROUND: Systems biology approaches to study metabolic switching in Streptomyces coelicolor A3(2) depend on cultivation conditions ensuring high reproducibility and distinct phases of culture growth and secondary metabolite production. In addition, biomass concentrations must be sufficiently high...

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Detalles Bibliográficos
Autores principales: Wentzel, Alexander, Bruheim, Per, Øverby, Anders, Jakobsen, Øyvind M, Sletta, Håvard, Omara, Walid A M, Hodgson, David A, Ellingsen, Trond E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431225/
https://www.ncbi.nlm.nih.gov/pubmed/22676814
http://dx.doi.org/10.1186/1752-0509-6-59