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Sufficient virus-neutralizing antibody in the central nerve system improves the survival of rabid rats
BACKGROUND: Rabies is known to be lethal in human. Treatment with passive immunity for the rabies is effective only when the patients have not shown the central nerve system (CNS) signs. The blood–brain barrier (BBB) is a complex functional barrier that may compromise the therapeutic development in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431253/ https://www.ncbi.nlm.nih.gov/pubmed/22734518 http://dx.doi.org/10.1186/1423-0127-19-61 |