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A systems biology approach reveals common metastatic pathways in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents. The survival rate of patients with metastatic disease remains very dismal. Nevertheless, metastasis is a complex process and a single-level analysis is not likely to identify its key biological determi...

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Detalles Bibliográficos
Autores principales: Flores, Ricardo J, Li, Yiting, Yu, Alexander, Shen, Jianhe, Rao, Pulivarthi H, Lau, Serrine S, Vannucci, Marina, Lau, Ching C, Man, Tsz-Kwong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431263/
https://www.ncbi.nlm.nih.gov/pubmed/22640921
http://dx.doi.org/10.1186/1752-0509-6-50