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A comparative transcriptomic, fluxomic and metabolomic analysis of the response of Saccharomyces cerevisiae to increases in NADPH oxidation

BACKGROUND: Redox homeostasis is essential to sustain metabolism and growth. We recently reported that yeast cells meet a gradual increase in imposed NADPH demand by progressively increasing flux through the pentose phosphate (PP) and acetate pathways and by exchanging NADH for NADPH in the cytosol,...

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Detalles Bibliográficos
Autores principales: Celton, Magalie, Sanchez, Isabelle, Goelzer, Anne, Fromion, Vincent, Camarasa, Carole, Dequin, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431268/
https://www.ncbi.nlm.nih.gov/pubmed/22805527
http://dx.doi.org/10.1186/1471-2164-13-317