Chronotolerance study of the antiepileptic drug valproic acid in mice

BACKGROUND: Valproic acid (VPA) is an antiepileptic drug widely used for the treatment of absence seizures and generalized tonic-clonic seizures. The present work aims to study whether VPA-induced toxicity varies according to the dosing-time in the 24 hour-scale. METHODS: The influence of dosing-tim...

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Detalles Bibliográficos
Autores principales: Ben-Cherif, Wafa, Dridi, Ichrak, Aouam, Karim, Ben-Attia, Mossadok, Reinberg, Alain, Boughattas, Naceur A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431278/
https://www.ncbi.nlm.nih.gov/pubmed/22574933
http://dx.doi.org/10.1186/1740-3391-10-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431278/
https://www.ncbi.nlm.nih.gov/pubmed/22574933
http://dx.doi.org/10.1186/1740-3391-10-3

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