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Chronotolerance study of the antiepileptic drug valproic acid in mice

BACKGROUND: Valproic acid (VPA) is an antiepileptic drug widely used for the treatment of absence seizures and generalized tonic-clonic seizures. The present work aims to study whether VPA-induced toxicity varies according to the dosing-time in the 24 hour-scale. METHODS: The influence of dosing-tim...

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Detalles Bibliográficos
Autores principales:	Ben-Cherif, Wafa, Dridi, Ichrak, Aouam, Karim, Ben-Attia, Mossadok, Reinberg, Alain, Boughattas, Naceur A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431278/ https://www.ncbi.nlm.nih.gov/pubmed/22574933 http://dx.doi.org/10.1186/1740-3391-10-3

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