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Teasing Apart Translational and Transcriptional Components of Stochastic Variations in Eukaryotic Gene Expression

The intrinsic stochasticity of gene expression leads to cell-to-cell variations, noise, in protein abundance. Several processes, including transcription, translation, and degradation of mRNA and proteins, can contribute to these variations. Recent single cell analyses of gene expression in yeast hav...

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Detalles Bibliográficos
Autores principales: Salari, Raheleh, Wojtowicz, Damian, Zheng, Jie, Levens, David, Pilpel, Yitzhak, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431295/
https://www.ncbi.nlm.nih.gov/pubmed/22956896
http://dx.doi.org/10.1371/journal.pcbi.1002644