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Interplay of Gene Expression Noise and Ultrasensitive Dynamics Affects Bacterial Operon Organization
Bacterial chromosomes are organized into polycistronic cotranscribed operons, but the evolutionary pressures maintaining them are unclear. We hypothesized that operons alter gene expression noise characteristics, resulting in selection for or against maintaining operons depending on network architec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431296/ https://www.ncbi.nlm.nih.gov/pubmed/22956903 http://dx.doi.org/10.1371/journal.pcbi.1002672 |