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Human Monoclonal Antibody HCV1 Effectively Prevents and Treats HCV Infection in Chimpanzees

Hepatitis C virus (HCV) infection is a leading cause of liver transplantation and there is an urgent need to develop therapies to reduce rates of HCV infection of transplanted livers. Approved therapeutics for HCV are poorly tolerated and are of limited efficacy in this patient population. Human mon...

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Detalles Bibliográficos
Autores principales: Morin, Trevor J., Broering, Teresa J., Leav, Brett A., Blair, Barbra M., Rowley, Kirk J., Boucher, Elisabeth N., Wang, Yang, Cheslock, Peter S., Knauber, Michael, Olsen, David B., Ludmerer, Steve W., Szabo, Gyongyi, Finberg, Robert W., Purcell, Robert H., Lanford, Robert E., Ambrosino, Donna M., Molrine, Deborah C., Babcock, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431327/
https://www.ncbi.nlm.nih.gov/pubmed/22952447
http://dx.doi.org/10.1371/journal.ppat.1002895